Endocrine Abstracts

Background: The purpose of this study was to investigate the occurrence of autoimmune thyroid disease in children and adolescents at onset of type 1 diabetes mellitus (T1DM) and to assess whether the presence of diabetes-specific autoantibodies may predict the autoimmune thyroid disorder.Methods: Seventy-three children with T1DM were recruited in the study. Glutamic acid decarboxylase antibodies (GADA), Islet cell antibodies (ICA), insulin autoantibodies...

Background: We investigated the frequency of autoimmune thyroid and diabetes antibodies in patients with type 1 diabetes mellitus (T1DM), their siblings, and controls.Methods: Glutamic acid decarboxylase antibodies (GADA), islet cell antibodies (ICA), insulin autoantibodies (IAA), and thyroid antibodies were identified in all subjects.Results: The rates of positive GADA and IAA were significantly higher in probands compared to sibl...